

Horizontal and vertical folds, small paper loss where seal torn on address leaf (neatly restored), address leaf within narrow paper border.
"Your treatment of Dr. Willard's case was judicious. The remains of his disease will I hope yield to moderately depleting, and tonic remedies according to the State of his pulse. Coffee should not be tasted by him. An issue in his arm may be useful.
"The Case of Hydrocephalus described in your letter is a curious one. I fear medicine can do nothing for it."